Chemistry for Biotech I

Description

Objectives in terms of knowledge (course content :
 

• General Chemistry : atomic and molecular properties, hybridations, VSEPR, acides, bases, organic oxydo-reductions, nucleophile/electrophile. Dipoles and non covalent interactions, energetic aspects of chemical reactions, Hammond’s postulate, Curtin-Hammet principle.
• Stereochemistry : determination of relative and absolute configurations, enantiomers, diastereoisomers, meso compound, prochirality, aspects of stereoselectivity, conformational analysis.
• Organic Chemistry: Formation and reactivity of the main organic functions: carbonyle, acide and acide derivatives, alkene, alkyne, amine-imine, alcohol. Chemo- and regioselectivity. Aromatic and heteroaromatic chemistry.
• Basic bioorganic chemistry : sugars, lipides, aminoacides and peptides, nucleotides/nucleosides.

Compétences visées

Objectives in terms of skills :

• Acquisition of the basic notions of organic chemistry as a theoretical to understand metabolic conversions and biochemistry.

Bibliographie

Bibliography :

• Chimie Organique Avancée (Tome1 et 2), Carey, Sundberg, De Boeck Université.
• Stereochemistry of Organic Compounds, Eliel, Wiley and Sons Eds.
• Chimie Organique J. Clayden, N. Greeves, S. Warren, P. Wothers De Boeck Université.

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